Torino will face a tough test to make it to the Europa League group stage, after they suffered a 1st leg defeat against Wolves at the Stadio Grande Torino on Thursday night.
With Iago Falque injured, Simone Zaza and Andrea Belotti continued up front with Alex Berenguer supporting in a 3-4-1-2 formation.
Wolves had the first chance of the game, with right wing back Adama Traore causing problems for Torino, and his low cross found Diogo Jota, but Salvatore Sirigu produced a good save with his legs.
At the other end, Nicolas Nkoulou hit the crossbar with a header following an inch perfect cross from Armando Izzo. It was then Izzo himself who went close to giving Torino the lead, but he was denied by Rui Patricio.
On the stroke of half time, Wolves took the lead as Joao Moutinho's excellent free kick delivery was headed into his own net by Bremer.
On the hour mark, Wolves doubled their lead when Traore, causing havoc on the right, again found Diogo Jota in the area, and this time he made no mistake.
However, Torino immediately pulled a goal back when Cristian Ansaldi's excellent cross found Lorenzo De Silvestri who headed into the net.
Wolves re-established their two goal advantage ten minutes later when some hesitant Toro defending allowed Raul Jimenez to add a third goal.
Just when it seemed Torino's European adventure was going to be over, they were handed a lifeline when Ruben Vinagre upended Andrea Belotti in the area. The Toro captain stepped up and fired past Patricio to reduce the deficit once again.
In injury time, Belotti almost conjured up an incredible equaliser, but his long range effort was tipped round the post by Patricio.
Torino have now left themselves a difficult, but not impossible task to achieve in Wolverhampton as they must win by two clear goals in order to reach the group stage.