Torino lost their first match since the Serie A restart after a disappointing 4-2 defeat in Sardinia on Saturday evening.
Toro were behind after only twelve minutes when Uruguayan midfielder Nahitan Nandez volleyed home following a corner. The home side then doubled their lead five minutes later when Giovanni Simeone swept home from close range, with the goal initially being disallowed for offside before being allowed by VAR.
Toro felt like they should have been awarded a penalty before half time when Andrea Belotti was seemingly upended in the area by Lykogiannis, but the referee waved away the Granata's appeals.
It almost got worse before the break, when the referee initially gave Cagliari a penalty when Nicolas Nkoulou appeared to handle the ball in the area, however VAR confirmed that the ball hit the defender's shoulder.
However, a minute into the 2nd half, things did get worse for Toro when Radja Nainggolan scored from outside the area.
The introduction of Cristian Ansaldi gave Toro and immediate boost, and the Argentine's deep cross found Ola Aina whose cushioned header found Bremer, who finished well to reduce the deficit.
Hopes of an unlikely comeback were then made possible just five minutes later, when Simone Verdi's corner found Andrea Belotti, and the Toro captain volleyed home sensationally.
However, those hopes were quickly extinguished when Nicolas Nkoulou upended Luca Pellegrini in the area. Joao Pedro stepped up and sent Salvatore Sirigu the wrong way, as the home side claimed the victory in an entertaining game.